May 2019CIOAPPLICATIONS.COM8Aligning with the Trends Impacting the Life Science IndustryMARK HOFFMAN, CHIEF RESEARCH INFORMATION OFFICER, CHILDREN'S MERCY HOSPITALWhat kind of trends have you been witnessing lately in the life science space?This is a very exciting time at the intersection between the Life Sciences and information technology. New instruments and methods, such as next generation sequencing, generate increasingly complex data that requires collaboration and innovation in order to be applied in practice. For example,at Children's Mercy Hospitalwe have the Center for Pediatric Genomic Medicine. They sequence genomes to assist with complex diagnoses and research. Each sequencing read generates about a terabyte of data and we have completedmore than 10,000of these tests here. The data management and analysis requirements to support this workflow are complex.Our high-performance computing and bioinformatics teams work closely together and collaborate with the clinicians to optimize this complex process. There are unmet opportunities to integrate the results of these tests into clinical systems. And new advances such as single cell sequencing will continue to push the envelope of the technical infrastructure.Could you elaborate on some interesting and impactful initiatives that you're currently overseeing?I lead a variety of initiatives related to the analysis of de-identified clinical data. We have developed a data platform for this resource using Microsoft Azure to support work with this large-scale data resource. A growing group of clinical IN MY View
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