AUGUST 2019CIOAPPLICATIONS.COM9group of patients. Joyable and Meru Health are up and coming DTx services in the mental health space. With chronic disease prevention and management becoming an imperative for population health management programs, companies like Omada health, Fruit Street, Solera Health, Canary Health, Noom, Blue Mesa and several others, leverage on evidence-based guidelines like the Center for Disease Control (CDC)'s National Diabetes Prevention Program. For diabetic patients, an app called Insulia from voluntis can let physicians remotely monitor progress and set up treatment plan rules that will adjust basal insulin dosing based on the patient's specific needs. Novo Nordisk, the maker of Insulin NovoPen, is releasing a companion app with the next iteration of its smart NovoPens. Glooko, a partner with Novo Nordisk in the diabetes space, recently got FDA approval for its Mobile Insulin Dosing system that can titrate long-acting insulin for patients with type 2 diabetes. BlueStar by Welldoc is a DTx for diabetes that is clinically validated with 40+ peer-reviewed publications and posters. Their randomized controlled trials proved an A1c improvement of 1.7 -2.0 when integrated with traditional care. AbbVie has a companion app called Complete that is a medication tracker and a patient resource for patients on Humira and Skyrizi.Sooner or later, our physicians will need an avenue through our patient portals to prescribe these apps. Patients will demand integration of these apps and digital therapies with the digital front door. The DTx space is expanding and maturing. The pharma industry is bullish on this category as it is cheaper and faster to create software than drugs. The software can also help a pharma company strategically extend a patent of a drug. Future states of DTx software may include integration with mobile health platforms, the addition of diagnostic or adjunct interventions, pairing with sensors and devices, and integration into electronic medical record platforms with an augmented or artificial intelligence layer. There has been a flurry of activity in the industry in the past few years. The Digital Health Alliance has emerged as a non-profit trade association engaged in evidence-driven advancement of DTx. For clinical validation, NODE. Health has emerged as the network for Digital Evidence in health with 20+ healthcare systems as partners. The advent of this new class of interventions and the general rise of consumerism presents an opportunity for CXOs to take a more in-depth look at their digital strategy. The healthcare consumers of today in addition to traditional brick and mortar, and mail-order pharmacies, also need a virtual door to get their digital therapeutic apps. It may be time to look at your digital front door from a new perspective and build capabilities to enable DTx. Digital Therapeutics is a class of interventions that include software programs used independently or in concert with medications, devices, and other therapies to improve outcomes
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